1st CAR T-cell therapy for cancer patients launched

Mumbai : President Droupadi Murmu on Thursday launched India's first indigenously-developed CAR T-cell therapy for cancer treatment, hailing it as a major breakthrough that provides "new hope for humankind" in the battle against the disease. Developed by the Indian Institute of Technology (IIT) Bombay and Tata Memorial Centre, the gene-based therapy is being rolled out in India at about one-tenth of its price outside the country, a senior official said.

Speaking at the launch event at IIT Bombay here, Murmu said the indigenous development of the therapy was an example of the Make in India initiative. A CAR T-cell therapy involves modifying a patient's T cells (a type of immune system cell) in the laboratory and using them to attack and destroy cancer cells. The `NexCAR19 CAR T-cell therapy' is the country's first 'Made in India' CAR T-cell therapy which is expected to bring down the cost of treatment significantly. This therapy is considered a phenomenal advance in medical sciences, the president said in her speech. "The development of this therapy is also an example of the 'Make in India' initiative and speaks volumes about Indian scientists and physicians," she said.

"The launch of India's first gene therapy is a major breakthrough in our battle against cancer. As this line of treatment, named CAR T-cell therapy, is accessible and affordable, it provides a new hope for the whole of humankind," Murmu added. Sudeep Gupta, director of the Tata Memorial Centre, said the CAR T-cell therapy was enormously expensive and out of the reach of an overwhelming majority of people.

NexCar19 needs to be custom manufactured for every patient under the most stringent conditions, but it has been rolled out at approximately one-tenth of the price at which it is available outside India, he said. IIT Bombay director Prof Subhasis Chaudhuri said the treatment costs approximately Rs 4 crore abroad against Rs 30 lakh in India.